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Author Question: What preoperative therapy is effective in a diagnosed sickle cell patient? a. Stem cell ... (Read 132 times)

RODY.ELKHALIL

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on: Jun 25, 2018
What preoperative therapy is effective in a diagnosed sickle cell patient?
 
  a. Stem cell transplant
  b. Transfusion of red blood cells
  c. Hydroxyurea administration
  d. Gene therapy

Question 2

Other than hemoglobin S, name two abnormal hemoglobins that produce a positive sickle solubility test. Explain how they could be differentiated from HbS.
 
  What will be an ideal response?


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pratush dev

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Reply #1 on: Jun 25, 2018
Answer to Question 1

Correct Answer: B

Answer to Question 2

Answer: Hemoglobins C-Harlem and HbI have positive sickle solubility tests (they share the same mutation as hemoglobin S-valine for glutamic at the beta-6 position plus an additional amino acid substitution). To differentiate these from Hb S, hemoglobin electrophoresis should be performed.


RODY.ELKHALIL

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Reply 2 on: Jun 25, 2018
Thanks for the timely response, appreciate it

sarah_brady415

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Reply 3 on: Yesterday
Great answer, keep it coming :)

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