This topic contains a solution. Click here to go to the answer
« previous next »

Author Question: Which of the following describes how platelet clumping artificially alters platelet parameters? ... (Read 69 times)

sjones

  • Hero Member
  • *****
  • Posts: 520
on: Jun 25, 2018
Which of the following describes how platelet clumping artificially alters platelet parameters?
 
  a. Increases both the PDW and the MPV
  b. Decreases both the PDW and the MPV
  c. Increases the PDW and decreases the MPV
  d. Decreases the PDW and increases the MPV

Question 2

Identify the major cytokines that regulate platelet production and describe their effects on megakaryocytic cells and circulating platelets.
 
  What will be an ideal response?


Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by a Subject Expert

amy.lauersdorf90

  • Sr. Member
  • ****
  • Posts: 327
Reply #1 on: Jun 25, 2018
Answer to Question 1

Correct Answer: A

Answer to Question 2

Answer: All stages of megakaryocyte development are influenced by TPO including megakaryocyte survival, proliferation, the ploidy level, and the rate of maturation. Stromal cell-derived factor-1 (SDF-1) augments TPO-induced megakaryocyte growth and endothelial adhesion within the marrow microenvironment. TPO also regulates the number of platelets in the peripheral blood. TPO binds to the c-Mpl receptor on platelets in circulation, is internalized, and is degraded to regulate the amount of TPO that can influence platelet progenitors.
Megakaryocyte progenitors proliferate in the presence of IL-3, GM-CSF, stem cell factor, and Flt ligand, whereas megakaryocyte maturation is influenced by IL-6 and
IL-7 (with other cytokines). Transforming growth factor- (TGF-) and -interferon (IFN-) both inhibit megakaryopoiesis.


sjones

  • Member
  • Posts: 520
Reply 2 on: Jun 25, 2018
Gracias!

yeungji

  • Member
  • Posts: 319
Reply 3 on: Yesterday
Great answer, keep it coming :)

« previous next »
 

Did you know?

By definition, when a medication is administered intravenously, its bioavailability is 100%.

Did you know?

Calcitonin is a naturally occurring hormone. In women who are at least 5 years beyond menopause, it slows bone loss and increases spinal bone density.

Did you know?

Alzheimer's disease affects only about 10% of people older than 65 years of age. Most forms of decreased mental function and dementia are caused by disuse (letting the mind get lazy).

Did you know?

There used to be a metric calendar, as well as metric clocks. The metric calendar, or "French Republican Calendar" divided the year into 12 months, but each month was divided into three 10-day weeks. Each day had 10 decimal hours. Each hour had 100 decimal minutes. Due to lack of popularity, the metric clocks and calendars were ended in 1795, three years after they had been first marketed.

Did you know?

Certain chemicals, after ingestion, can be converted by the body into cyanide. Most of these chemicals have been removed from the market, but some old nail polish remover, solvents, and plastics manufacturing solutions can contain these substances.

Platelet structure. Platelet structure.
One view of inclination i (green) and other orbital parameters One view of inclination i (green) and other orbital parameters
Glycoprotein IIb/IIIa receptor activation of platelet function. Glycoprotein IIb/IIIa receptor activation of platelet function.
A dose-response curve describes the relationship between the quantity of the chemical entering the ... A dose-response curve describes the relationship between the quantity of the chemical entering the ...
Parameters of Polynucleotide Helices Parameters of Polynucleotide Helices
Platelet-activating factor Platelet-activating factor
Video: Muscle Twitch and Muscle Tension - Motor unit size and force

For a complete list of videos, visit our video library