Author Question: Compare and contrast the HSC and the progenitor cells. How are they similar? How are they different? ... (Read 89 times)

sdfghj

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Compare and contrast the HSC and the progenitor cells. How are they similar? How are they different?
 
  What will be an ideal response?

Question 2

Which of the following best describes the phenotype of the hematopoietic stem cell?
 
  a. CD34+ CD38+Lin-HLA-DR-Rh123Bright, SCF-R+,TPO-R+
  b. CD34+ CD33+CD38+Lin- Rh123Lo
  c. CD34+ CD38-Lin-HLA-DR-Rh123Lo, SCF-R+,TPO-R+
  d. CD3+,CD4+,CD5+,CD8+,CD38-,HLA-DR-



upturnedfurball

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Answer to Question 1

Answer: The hematopoietic stem cell (HSC) has capabilities of self-renewal, and helps give rise to progenitor cells that will create the sequence of blood cell maturation. The main difference between the HSC and the progenitors is their outcomes. The HSC has the capability to give rise to any of the blood cell lineages, whereas the progenitors are more restricted in their ability to produce different types of blood cells. The two types of cell are morphologically indistinguishable.

Answer to Question 2

Correct answer: C



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