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By definition, when a medication is administered intravenously, its bioavailability is 100%.
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In 1844, Charles Goodyear obtained the first patent for a rubber condom.
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It is believed that the Incas used anesthesia. Evidence supports the theory that shamans chewed cocoa leaves and drilled holes into the heads of patients (letting evil spirits escape), spitting into the wounds they made. The mixture of cocaine, saliva, and resin numbed the site enough to allow hours of drilling.
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HIV testing reach is still limited. An estimated 40% of people with HIV (more than 14 million) remain undiagnosed and do not know their infection status.
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About 100 new prescription or over-the-counter drugs come into the U.S. market every year.