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Hippocrates noted that blood separates into four differently colored liquids when removed from the body and examined: a pure red liquid mixed with white liquid material with a yellow-colored froth at the top and a black substance that settles underneath; he named these the four humors (for blood, phlegm, yellow bile, and black bile).
The B-complex vitamins and vitamin C are not stored in the body and must be replaced each day.
In Eastern Europe and Russia, interferon is administered intranasally in varied doses for the common cold and influenza. It is claimed that this treatment can lower the risk of infection by as much as 60–70%.
After 5 years of being diagnosed with rheumatoid arthritis, one every three patients will no longer be able to work.
In 1864, the first barbiturate (barbituric acid) was synthesized.