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The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
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Addicts to opiates often avoid treatment because they are afraid of withdrawal. Though unpleasant, with proper management, withdrawal is rarely fatal and passes relatively quickly.
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Immunoglobulin injections may give short-term protection against, or reduce severity of certain diseases. They help people who have an inherited problem making their own antibodies, or those who are having certain types of cancer treatments.
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In 1844, Charles Goodyear obtained the first patent for a rubber condom.
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Most childhood vaccines are 90–99% effective in preventing disease. Side effects are rarely serious.