Answer to Question 1
Correct Answer: 1, 2, 4, 5
Atrophic changes are changes in the size or activity of body tissues resulting from pathology or injury. Reduced blood flow and oxygenation of the lower extremities often cause atrophic changes, including loss of hair, thickened toenails, changes in pigmentation, and ulcerations. Dilated leg veins are related to varicose veins.
Answer to Question 2
Correct Answer: 1, 3, 4
Gaucher disease, more common in descendants of Eastern European Jewish people, is an inherited illness caused by a gene mutation. The gene is responsible for an enzyme that breaks down a specific fat. When the fat is not broken down, it accumulates in the liver, spleen, and bone marrow, causing pain, fatigue, jaundice, bone damage, anemia, and even death. Nausea and hypotension are not manifestations of Gaucher disease.