Clinical manifestations of ischemic hepatitis show up 1 to 2 days ...

[DelorasTo]

Clinical manifestations of ischemic hepatitis show up 1 to 2 days after the insult. Which symptom below is indicative of hepatic insufficiency?
 
  a. Elevated serum creatinine
  b. Decreased bilirubin
  c. Jaundice
  d. Decreased serum transaminase

Question 2

Place these pathophysiologic mechanisms of DIC in the order in which they occur
 
  1 . Activation of the fibrinolytic system
  2 . Breakdown of thrombi; spontaneous hemorrhage
  3 . Consumption of coagulation factors; failure of regulatory mechanisms
  4 . Endothelial damage; release of tissue factor
  5 . Thrombin formation; clots form along epithelial walls
 
  a. 4, 1, 5, 2, 3
  b. 4, 1, 3, 2, 5
  c. 5, 1, 2, 4, 3
  d. 2, 3, 1, 5, 4

[whitcassie]

Answer to Question 1

C
Clinical manifestations of hepatic insufficiency are evident 1 to 2 days after the insult. Jaundice and transient elevations in serum transaminase and bilirubin levels occur. Hyperbilirubinemia results from hepatocyte anoxic injury and an increased production of bilirubin from hemoglobin catabolism.

Answer to Question 2

A
Endothelial damage triggers the release of tissue factor. Thrombin is released, and clots form, consuming coagulation factors. The fibrinolytic system is triggered to break down the clots, which leads to spontaneous hemorrhage.