Four clients are receiving tyrosine kinase inhibitors (TKIs). ...

[APUS57]

Four clients are receiving tyrosine kinase inhibitors (TKIs). Which of these four clients should the nurse assess first?
 
  a. Client with dry, itchy, peeling skin
  b. Client with a serum calcium of 9.2 mg/dL
  c. Client with a serum potassium of 2.8 mEq/L
  d. Client with a weight gain of 0.5 pound (1.1 kg) in 1 day

Question 2

A nurse is assessing a female client who is taking progestins. What assessment finding requires the nurse to notify the provider immediately?
 
  a. Irregular menses
  b. Edema in the lower extremities
  c. Ongoing breast tenderness
  d. Red, warm, swollen calf

[mcabuhat]

Answer to Question 1

ANS: C
TKIs can cause electrolyte imbalances. This potassium level is very low, so the nurse should assess this client first. Dry, itchy, peeling skin can be a problem in clients receiving biologic response modifiers, and the nurse should assess that client next because of the potential for discomfort and infection. This calcium level is normal. TKIs can also cause weight gain, but the client with the low potassium level is more critical.

Answer to Question 2

ANS: D
All clients receiving progestin therapy are at risk for thromboembolism. A red, warm, swollen calf is a manifestation of deep vein thrombosis and should be reported to the provider. Irregular menses, edema in the lower extremities, and breast tenderness are common side effects of the therapy.