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In 1864, the first barbiturate (barbituric acid) was synthesized.
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The Romans did not use numerals to indicate fractions but instead used words to indicate parts of a whole.
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Disorders that may affect pharmacodynamics include genetic mutations, malnutrition, thyrotoxicosis, myasthenia gravis, Parkinson's disease, and certain forms of insulin-resistant diabetes mellitus.
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Women are 50% to 75% more likely than men to experience an adverse drug reaction.
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Opium has influenced much of the world's most popular literature. The following authors were all opium users, of varying degrees: Lewis Carroll, Charles, Dickens, Arthur Conan Doyle, and Oscar Wilde.