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In women, pharmacodynamic differences include increased sensitivity to (and increased effectiveness of) beta-blockers, opioids, selective serotonin reuptake inhibitors, and typical antipsychotics.
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Most childhood vaccines are 90–99% effective in preventing disease. Side effects are rarely serious.
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Cancer has been around as long as humankind, but only in the second half of the twentieth century did the number of cancer cases explode.
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Oliver Wendell Holmes is credited with introducing the words "anesthesia" and "anesthetic" into the English language in 1846.