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In 1864, the first barbiturate (barbituric acid) was synthesized.
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The FDA recognizes 118 routes of administration.
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Drug-induced pharmacodynamic effects manifested in older adults include drug-induced renal toxicity, which can be a major factor when these adults are experiencing other kidney problems.
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About 60% of newborn infants in the United States are jaundiced; that is, they look yellow. Kernicterus is a form of brain damage caused by excessive jaundice. When babies begin to be affected by excessive jaundice and begin to have brain damage, they become excessively lethargic.
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Multiple experimental evidences have confirmed that at the molecular level, cancer is caused by lesions in cellular DNA.