Through genetic testing a homosexual male learns of having two ...

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Through genetic testing a homosexual male learns of having two copies of a gene deleted in gene CCR5. What should the nurse prepare to discuss with this client? Select all that apply.
 
  1. Safe sexual practices
  2. Reduced risk of contracting HIV
  3. Increased risk of contracting HIV
  4. Expectation to develop AIDs quickly
  5. Delayed conversion of HIV to AIDS

Question 2

The nurse notes that a client is admitted for treatment of a disease caused by a single-nucleotide genetic disorder. For which health problem should the nurse plan care for this client?
 
  1. Cancer
  2. Heart disease
  3. Sickle cell anemia
  4. Huntington disease

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Answer to Question 1

1, 2
Explanation:
1. Even though persons who have two copies of the altered CCR5 gene are almost completely resistant to infection with HIV type 1, the client should still be reminded of safe sexual practices.
2. Persons who have two copies of the altered CCR5 gene are almost completely resistant to infection with HIV type 1.
3. The client does not have an increased risk for contracting HIV.
4. Two copies of the altered CCR5 gene will not accelerate the development of AIDS from HIV.
5. Clients who have one copy of the altered CCR5 gene will have delayed conversion of HIV to AIDS.

Answer to Question 2

3
Explanation:
1. Cancer can be caused by either a somatic mutation or a multifactorial disorder.
2. Heart disease is considered a multifactorial disorder.
3. Alterations as small as a single-nucleotide change are known to cause disease. Sickle cell disease is such a disorder.
4. Huntington disease is caused by trinucleotide repeat expansion disorder.