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More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.
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More than 20 million Americans cite use of marijuana within the past 30 days, according to the National Survey on Drug Use and Health (NSDUH). More than 8 million admit to using it almost every day.
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About 100 new prescription or over-the-counter drugs come into the U.S. market every year.
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Signs and symptoms of a drug overdose include losing consciousness, fever or sweating, breathing problems, abnormal pulse, and changes in skin color.
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The average adult has about 21 square feet of skin.