Chloramphenicol is an antibiotic that targets prokaryotic (70S) ribosomes, but not eukaryotic (80S) ribosomes. Which of these questions stems from this observation, plus an understanding of eukaryotic origins?
A) Can chloramphenicol also be used to control human diseases that are caused by archaeans?
B) Can chloramphenicol pass through the capsules possessed by many cyanobacteria?
C) If chloramphenicol inhibits prokaryotic ribosomes, should it not also inhibit mitochondrial ribosomes?
D) Why aren't prokaryotic ribosomes identical to eukaryotic ribosomes?
E) How is translation affected in ribosomes that are targeted by chloramphenicol?
The cell membrane, cytoplasm, nucleus, nucleolus, ribosomes, centrioles, and mitochondria.
Part of a written prescription prescribing an antibiotic for a dental infection.
Components of bacterial and eukaryotic ribosomes
A schematic view of ribosome subunit rotational motions, based on crystal structures of ribosomes
Translation at endoplasmic reticulum–bound ribosomes and the signal hypothesis
Antibiotic Inhibitors of Protein Synthesis