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Coca-Cola originally used coca leaves and caffeine from the African kola nut. It was advertised as a therapeutic agent and "pickerupper." Eventually, its formulation was changed, and the coca leaves were removed because of the effects of regulation on cocaine-related products.
The Romans did not use numerals to indicate fractions but instead used words to indicate parts of a whole.
The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
For pediatric patients, intravenous fluids are the most commonly cited products involved in medication errors that are reported to the USP.
Computer programs are available that crosscheck a new drug's possible trade name with all other trade names currently available. These programs detect dangerous similarities between names and alert the manufacturer of the drug.