The nurse is conducting a staff in-service on childhood blood ...

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The nurse is conducting a staff in-service on childhood blood disorders. Which describes the pathology of idiopathic thrombocytopenic purpura?
 
  a. Bone marrow failure in which all elements are suppressed
  b. Deficiency in the production rate of globin chains
  c. Diffuse fibrin deposition in the microvasculature
  d. An excessive destruction of platelets

Question 2

Parents of a hemophiliac child ask the nurse, Can you describe hemophilia to us? Which response by the nurse is descriptive of most cases of hemophilia?
 
  a. Autosomal dominant disorder causing deficiency in a factor involved in the blood-clotting reaction
  b. X-linked recessive inherited disorder causing deficiency of platelets and prolonged bleeding
  c. X-linked recessive inherited disorder in which a blood-clotting factor is deficient
  d. Y-linked recessive inherited disorder in which the red blood cells become moon-shaped

[AngeliqueG]

Answer to Question 1

ANS: D
Idiopathic thrombocytopenic purpura is an acquired hemorrhagic disorder characterized by an excessive destruction of platelets, discolorations caused by petechiae beneath the skin, and a normal bone marrow. Aplastic anemia refers to a bone marrowfailure condition in which the formed elements of the blood are simultaneously depressed. Thalassemia major is a group of blood disorders characterized by deficiency in the production rate of specific hemoglobin globin chains. Disseminated intravascular coagulation is characterized by diffuse fibrin deposition in the microvasculature, consumption of coagulation factors, and endogenous generation of thrombin and plasma.

Answer to Question 2

ANS: C
The inheritance pattern in 80 of all of the cases of hemophilia is X-linked recessive. The two most common forms of the disorder are factor VIII deficiency, hemophilia A or classic hemophilia; and factor IX deficiency, hemophilia B or Christmas disease. The inheritance pattern is X-linked recessive. The disorder involves coagulation factors, not platelets, and does not involve red cells or the Y chromosomes.

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Thanks for the timely response, appreciate it

[ttt030911]

TYSM