Author Question: What statement is descriptive of most cases of hemophilia? a. X-linked recessive deficiency of ... (Read 128 times)

michelleunicorn · **on:** Jun 28, 2018

What statement is descriptive of most cases of hemophilia?

a. X-linked recessive deficiency of platelets causing prolonged bleeding
b. X-linked recessive inherited disorder in which a blood clotting factor is deficient
c. Autosomal dominant deficiency of a factor involved in the blood-clotting reaction
d. Y-linked recessive inherited disorder in which the red blood cells become moon shaped

Question 2

For children who do not have a matched sibling bone marrow donor, the therapeutic management of aplastic anemia includes what intervention?

a. Antibiotics
b. Antiretroviral drugs
c. Iron supplementation
d. Immunosuppressive therapy

shailee · **Reply #1 on:** Jun 28, 2018

Answer to Question 1

ANS: B
The inheritance pattern in 80 of all the cases of hemophilia is X-linked recessive. The two most common forms of the disorder are factor VIII deficiency (hemophilia A, or classic hemophilia) and factor IX deficiency (hemophilia B, or Christmas disease). The disorder involves coagulation factors, not platelets. The disorder does not involve red blood cells or the Y chromosome.

Answer to Question 2

ANS: D
It is thought that aplastic anemia may be an autoimmune disease. Immunosuppressive therapy, including antilymphocyte globulin, antithymocyte globulin, cyclosporine, granulocyte colony-stimulating factor, and methylprednisone, has greatly improved the prognosis for patients with aplastic anemia. Antibiotics are not indicated as the management. They may be indicated for infections. Antiretroviral drugs and iron supplementation are not part of the therapy.