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Persons who overdose with cardiac glycosides have a better chance of overall survival if they can survive the first 24 hours after the overdose.
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The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
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Cocaine was isolated in 1860 and first used as a local anesthetic in 1884. Its first clinical use was by Sigmund Freud to wean a patient from morphine addiction. The fictional character Sherlock Holmes was supposed to be addicted to cocaine by injection.
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Thyroid conditions cause a higher risk of fibromyalgia and chronic fatigue syndrome.
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In 1864, the first barbiturate (barbituric acid) was synthesized.