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ACTH levels are normally highest in the early morning (between 6 and 8 A.M.) and lowest in the evening (between 6 and 11 P.M.). Therefore, a doctor who suspects abnormal levels looks for low ACTH in the morning and high ACTH in the evening.
In 1835 it was discovered that a disease of silkworms known as muscardine could be transferred from one silkworm to another, and was caused by a fungus.
Cocaine was isolated in 1860 and first used as a local anesthetic in 1884. Its first clinical use was by Sigmund Freud to wean a patient from morphine addiction. The fictional character Sherlock Holmes was supposed to be addicted to cocaine by injection.
Bacteria have been found alive in a lake buried one half mile under ice in Antarctica.
The Romans did not use numerals to indicate fractions but instead used words to indicate parts of a whole.
![The Movius line separates regions of the world where Acheulean hand axes were made from regions wher](https://biology-forums.com/gallery/47/medium_275510_22_02_15_5_56_55_207692261.jpeg)
![A container with gasoline containing alcohol. Notice the separation line where the alcohol-water ...](https://biology-forums.com/gallery/29/medium_548020_25_05_17_1_36_24_293741305.png)