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According to the FDA, adverse drug events harmed or killed approximately 1,200,000 people in the United States in the year 2015.
About 100 new prescription or over-the-counter drugs come into the U.S. market every year.
Signs of depression include feeling sad most of the time for 2 weeks or longer; loss of interest in things normally enjoyed; lack of energy; sleep and appetite disturbances; weight changes; feelings of hopelessness, helplessness, or worthlessness; an inability to make decisions; and thoughts of death and suicide.
It is believed that the Incas used anesthesia. Evidence supports the theory that shamans chewed cocoa leaves and drilled holes into the heads of patients (letting evil spirits escape), spitting into the wounds they made. The mixture of cocaine, saliva, and resin numbed the site enough to allow hours of drilling.
The immune system needs 9.5 hours of sleep in total darkness to recharge completely.