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Most childhood vaccines are 90–99% effective in preventing disease. Side effects are rarely serious.
By definition, when a medication is administered intravenously, its bioavailability is 100%.
In most cases, kidneys can recover from almost complete loss of function, such as in acute kidney (renal) failure.
Amphetamine poisoning can cause intravascular coagulation, circulatory collapse, rhabdomyolysis, ischemic colitis, acute psychosis, hyperthermia, respiratory distress syndrome, and pericarditis.
Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.