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On average, someone in the United States has a stroke about every 40 seconds. This is about 795,000 people per year.
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Disorders that may affect pharmacodynamics include genetic mutations, malnutrition, thyrotoxicosis, myasthenia gravis, Parkinson's disease, and certain forms of insulin-resistant diabetes mellitus.
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Between 1999 and 2012, American adults with high total cholesterol decreased from 18.3% to 12.9%
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Sildenafil (Viagra®) has two actions that may be of consequence in patients with heart disease. It can lower the blood pressure, and it can interact with nitrates. It should never be used in patients who are taking nitrates.
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Russia has the highest death rate from cardiovascular disease followed by the Ukraine, Romania, Hungary, and Poland.