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Signs of depression include feeling sad most of the time for 2 weeks or longer; loss of interest in things normally enjoyed; lack of energy; sleep and appetite disturbances; weight changes; feelings of hopelessness, helplessness, or worthlessness; an inability to make decisions; and thoughts of death and suicide.
Patients who cannot swallow may receive nutrition via a parenteral route—usually, a catheter is inserted through the chest into a large vein going into the heart.
In 1844, Charles Goodyear obtained the first patent for a rubber condom.
More than 150,000 Americans killed by cardiovascular disease are younger than the age of 65 years.
More than 30% of American adults, and about 12% of children utilize health care approaches that were developed outside of conventional medicine.

