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The Romans did not use numerals to indicate fractions but instead used words to indicate parts of a whole.
The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
In the United States, an estimated 50 million unnecessary antibiotics are prescribed for viral respiratory infections.
Though methadone is often used to treat dependency on other opioids, the drug itself can be abused. Crushing or snorting methadone can achieve the opiate "rush" desired by addicts. Improper use such as these can lead to a dangerous dependency on methadone. This drug now accounts for nearly one-third of opioid-related deaths.
Of the estimated 2 million heroin users in the United States, 600,000–800,000 are considered hardcore addicts. Heroin addiction is considered to be one of the hardest addictions to recover from.