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Nitroglycerin is used to alleviate various heart-related conditions, and it is also the chief component of dynamite (but mixed in a solid clay base to stabilize it).
According to the FDA, adverse drug events harmed or killed approximately 1,200,000 people in the United States in the year 2015.
The most destructive flu epidemic of all times in recorded history occurred in 1918, with approximately 20 million deaths worldwide.
Pope Sylvester II tried to introduce Arabic numbers into Europe between the years 999 and 1003, but their use did not catch on for a few more centuries, and Roman numerals continued to be the primary number system.
Cancer has been around as long as humankind, but only in the second half of the twentieth century did the number of cancer cases explode.