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There are major differences in the metabolism of morphine and the illegal drug heroin. Morphine mostly produces its CNS effects through m-receptors, and at k- and d-receptors. Heroin has a slight affinity for opiate receptors. Most of its actions are due to metabolism to active metabolites (6-acetylmorphine, morphine, and morphine-6-glucuronide).
After 5 years of being diagnosed with rheumatoid arthritis, one every three patients will no longer be able to work.
About 100 new prescription or over-the-counter drugs come into the U.S. market every year.
Approximately 500,000 babies are born each year in the United States to teenage mothers.
Intradermal injections are somewhat difficult to correctly administer because the skin layers are so thin that it is easy to accidentally punch through to the deeper subcutaneous layer.