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Bacteria have been found alive in a lake buried one half mile under ice in Antarctica.
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Earwax has antimicrobial properties that reduce the viability of bacteria and fungus in the human ear.
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Disorders that may affect pharmacodynamics include genetic mutations, malnutrition, thyrotoxicosis, myasthenia gravis, Parkinson's disease, and certain forms of insulin-resistant diabetes mellitus.
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Not getting enough sleep can greatly weaken the immune system. Lack of sleep makes you more likely to catch a cold, or more difficult to fight off an infection.
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Drying your hands with a paper towel will reduce the bacterial count on your hands by 45–60%.