Author Question: The phase of drug testing that includes determining toxicity, pharmacokinetics, and determining a ... (Read 137 times)

big1devin · **on:** Jul 3, 2018

The phase of drug testing that includes determining toxicity, pharmacokinetics, and determining a drugs therapeutic index occurs;

a. Postmarketing surveillance
b. New drug application
c. Clinical research and development
d. Preclinical testing, research, and development

Question 2

The tibia broadens at its distal end into what large process?

A) Lateral malleolus B) Medial malleolus C) Fibula D) Anterior crest

aprice35067 · **Reply #1 on:** Jul 3, 2018

Answer to Question 1

d

Rationale: a. Postmarketing surveillance occurs during phase four of testing. A new drugs therapeutic index must already be determined
b. An investigational new drug may be applied for once the therapeutic index has been determined prior to the phase 1 of human drug testing.
c. Clinical research and development begins after the therapeutic index has been determined.
d. Preclinical testing, research, and development occurs prior to human testing and is concerned with the pharmacokinetics and pharmacodynamics of a new drug in order to discover its therapeutic index.

Answer to Question 2

B