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There are major differences in the metabolism of morphine and the illegal drug heroin. Morphine mostly produces its CNS effects through m-receptors, and at k- and d-receptors. Heroin has a slight affinity for opiate receptors. Most of its actions are due to metabolism to active metabolites (6-acetylmorphine, morphine, and morphine-6-glucuronide).
By definition, when a medication is administered intravenously, its bioavailability is 100%.
After a vasectomy, it takes about 12 ejaculations to clear out sperm that were already beyond the blocked area.
Approximately one in three babies in the United States is now delivered by cesarean section. The number of cesarean sections in the United States has risen 46% since 1996.
More than 4.4billion prescriptions were dispensed within the United States in 2016.