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There are major differences in the metabolism of morphine and the illegal drug heroin. Morphine mostly produces its CNS effects through m-receptors, and at k- and d-receptors. Heroin has a slight affinity for opiate receptors. Most of its actions are due to metabolism to active metabolites (6-acetylmorphine, morphine, and morphine-6-glucuronide).
It is believed that humans initially contracted crabs from gorillas about 3 million years ago from either sleeping in gorilla nests or eating the apes.
The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
For pediatric patients, intravenous fluids are the most commonly cited products involved in medication errors that are reported to the USP.
There are 20 feet of blood vessels in each square inch of human skin.