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There are major differences in the metabolism of morphine and the illegal drug heroin. Morphine mostly produces its CNS effects through m-receptors, and at k- and d-receptors. Heroin has a slight affinity for opiate receptors. Most of its actions are due to metabolism to active metabolites (6-acetylmorphine, morphine, and morphine-6-glucuronide).
On average, someone in the United States has a stroke about every 40 seconds. This is about 795,000 people per year.
After 5 years of being diagnosed with rheumatoid arthritis, one every three patients will no longer be able to work.
There are over 65,000 known species of protozoa. About 10,000 species are parasitic.
More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.