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Excessive alcohol use costs the country approximately $235 billion every year.
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Vaccines prevent between 2.5 and 4 million deaths every year.
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In 1864, the first barbiturate (barbituric acid) was synthesized.
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Side effects from substance abuse include nausea, dehydration, reduced productivitiy, and dependence. Though these effects usually worsen over time, the constant need for the substance often overcomes rational thinking.
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Though the United States has largely rejected the metric system, it is used for currency, as in 100 pennies = 1 dollar. Previously, the British currency system was used, with measurements such as 12 pence to the shilling, and 20 shillings to the pound.