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There are major differences in the metabolism of morphine and the illegal drug heroin. Morphine mostly produces its CNS effects through m-receptors, and at k- and d-receptors. Heroin has a slight affinity for opiate receptors. Most of its actions are due to metabolism to active metabolites (6-acetylmorphine, morphine, and morphine-6-glucuronide).
Cancer has been around as long as humankind, but only in the second half of the twentieth century did the number of cancer cases explode.
More than 150,000 Americans killed by cardiovascular disease are younger than the age of 65 years.
The most common treatment options for addiction include psychotherapy, support groups, and individual counseling.
In ancient Rome, many of the richer people in the population had lead-induced gout. The reason for this is unclear. Lead poisoning has also been linked to madness.