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Interferon was scarce and expensive until 1980, when the interferon gene was inserted into bacteria using recombinant DNA technology, allowing for mass cultivation and purification from bacterial cultures.
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The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
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In Eastern Europe and Russia, interferon is administered intranasally in varied doses for the common cold and influenza. It is claimed that this treatment can lower the risk of infection by as much as 60–70%.
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In 1864, the first barbiturate (barbituric acid) was synthesized.
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Cyanide works by making the human body unable to use oxygen.