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Lower drug doses for elderly patients should be used first, with titrations of the dose as tolerated to prevent unwanted drug-related pharmacodynamic effects.
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Disorders that may affect pharmacodynamics include genetic mutations, malnutrition, thyrotoxicosis, myasthenia gravis, Parkinson's disease, and certain forms of insulin-resistant diabetes mellitus.
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The Romans did not use numerals to indicate fractions but instead used words to indicate parts of a whole.
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Between 1999 and 2012, American adults with high total cholesterol decreased from 18.3% to 12.9%
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Cancer has been around as long as humankind, but only in the second half of the twentieth century did the number of cancer cases explode.