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Cancer has been around as long as humankind, but only in the second half of the twentieth century did the number of cancer cases explode.
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The first oral chemotherapy drug for colon cancer was approved by FDA in 2001.
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In 1864, the first barbiturate (barbituric acid) was synthesized.
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Sildenafil (Viagra®) has two actions that may be of consequence in patients with heart disease. It can lower the blood pressure, and it can interact with nitrates. It should never be used in patients who are taking nitrates.
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About 3.2 billion people, nearly half the world population, are at risk for malaria. In 2015, there are about 214 million malaria cases and an estimated 438,000 malaria deaths.