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Intradermal injections are somewhat difficult to correctly administer because the skin layers are so thin that it is easy to accidentally punch through to the deeper subcutaneous layer.
Pope Sylvester II tried to introduce Arabic numbers into Europe between the years 999 and 1003, but their use did not catch on for a few more centuries, and Roman numerals continued to be the primary number system.
There are major differences in the metabolism of morphine and the illegal drug heroin. Morphine mostly produces its CNS effects through m-receptors, and at k- and d-receptors. Heroin has a slight affinity for opiate receptors. Most of its actions are due to metabolism to active metabolites (6-acetylmorphine, morphine, and morphine-6-glucuronide).
Illicit drug use costs the United States approximately $181 billion every year.
In the United States, an estimated 50 million unnecessary antibiotics are prescribed for viral respiratory infections.
![Nebulizer. The nebulizer converts a liquid medication to a mist that is easily inhaled. A face mask,](https://biology-forums.com/gallery/47/medium_14755_11_11_12_7_25_46_100642210.jpeg)
![Multiple-dose drug administration: drug A and drug B are administered every 12 hours; drug B reaches](https://biology-forums.com/gallery/47/medium_46687_12_12_14_7_07_22_19567430.jpeg)