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Parkinson's disease is both chronic and progressive. This means that it persists over a long period of time and that its symptoms grow worse over time.
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In most cases, kidneys can recover from almost complete loss of function, such as in acute kidney (renal) failure.
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Long-term mental and physical effects from substance abuse include: paranoia, psychosis, immune deficiencies, and organ damage.
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In women, pharmacodynamic differences include increased sensitivity to (and increased effectiveness of) beta-blockers, opioids, selective serotonin reuptake inhibitors, and typical antipsychotics.
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After a vasectomy, it takes about 12 ejaculations to clear out sperm that were already beyond the blocked area.