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The use of salicylates dates back 2,500 years to Hippocrates’s recommendation of willow bark (from which a salicylate is derived) as an aid to the pains of childbirth. However, overdosage of salicylates can harm body fluids, electrolytes, the CNS, the GI tract, the ears, the lungs, the blood, the liver, and the kidneys and cause coma or death.
Disorders that may affect pharmacodynamics include genetic mutations, malnutrition, thyrotoxicosis, myasthenia gravis, Parkinson's disease, and certain forms of insulin-resistant diabetes mellitus.
The calories found in one piece of cherry cheesecake could light a 60-watt light bulb for 1.5 hours.
More than 34,000 trademarked medication names and more than 10,000 generic medication names are in use in the United States.
By definition, when a medication is administered intravenously, its bioavailability is 100%.