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Disorders that may affect pharmacodynamics include genetic mutations, malnutrition, thyrotoxicosis, myasthenia gravis, Parkinson's disease, and certain forms of insulin-resistant diabetes mellitus.
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By definition, when a medication is administered intravenously, its bioavailability is 100%.
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The average human gut is home to perhaps 500 to 1,000 different species of bacteria.
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In most cases, kidneys can recover from almost complete loss of function, such as in acute kidney (renal) failure.
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The strongest synthetic topical retinoid drug available, tazarotene, is used to treat sun-damaged skin, acne, and psoriasis.