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Coca-Cola originally used coca leaves and caffeine from the African kola nut. It was advertised as a therapeutic agent and "pickerupper." Eventually, its formulation was changed, and the coca leaves were removed because of the effects of regulation on cocaine-related products.
In women, pharmacodynamic differences include increased sensitivity to (and increased effectiveness of) beta-blockers, opioids, selective serotonin reuptake inhibitors, and typical antipsychotics.
In the United States, an estimated 50 million unnecessary antibiotics are prescribed for viral respiratory infections.
For pediatric patients, intravenous fluids are the most commonly cited products involved in medication errors that are reported to the USP.
Urine turns bright yellow if larger than normal amounts of certain substances are consumed; one of these substances is asparagus.