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The longest a person has survived after a heart transplant is 24 years.
A good example of polar molecules can be understood when trying to make a cake. If water and oil are required, they will not mix together. If you put them into a measuring cup, the oil will rise to the top while the water remains on the bottom.
Certain chemicals, after ingestion, can be converted by the body into cyanide. Most of these chemicals have been removed from the market, but some old nail polish remover, solvents, and plastics manufacturing solutions can contain these substances.
Human kidneys will clean about 1 million gallons of blood in an average lifetime.
In most cases, kidneys can recover from almost complete loss of function, such as in acute kidney (renal) failure.