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In women, pharmacodynamic differences include increased sensitivity to (and increased effectiveness of) beta-blockers, opioids, selective serotonin reuptake inhibitors, and typical antipsychotics.
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Although puberty usually occurs in the early teenage years, the world's youngest parents were two Chinese children who had their first baby when they were 8 and 9 years of age.
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Everyone has one nostril that is larger than the other.
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The horizontal fraction bar was introduced by the Arabs.
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The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.