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Cocaine was isolated in 1860 and first used as a local anesthetic in 1884. Its first clinical use was by Sigmund Freud to wean a patient from morphine addiction. The fictional character Sherlock Holmes was supposed to be addicted to cocaine by injection.
More than 150,000 Americans killed by cardiovascular disease are younger than the age of 65 years.
Signs of depression include feeling sad most of the time for 2 weeks or longer; loss of interest in things normally enjoyed; lack of energy; sleep and appetite disturbances; weight changes; feelings of hopelessness, helplessness, or worthlessness; an inability to make decisions; and thoughts of death and suicide.
The Romans did not use numerals to indicate fractions but instead used words to indicate parts of a whole.
In the United States, an estimated 50 million unnecessary antibiotics are prescribed for viral respiratory infections.