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In 1864, the first barbiturate (barbituric acid) was synthesized.
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The first-known contraceptive was crocodile dung, used in Egypt in 2000 BC. Condoms were also reportedly used, made of animal bladders or intestines.
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Vaccines prevent between 2.5 and 4 million deaths every year.
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Historic treatments for rheumatoid arthritis have included gold salts, acupuncture, a diet consisting of apples or rhubarb, nutmeg, nettles, bee venom, bracelets made of copper, prayer, rest, tooth extractions, fasting, honey, vitamins, insulin, snow collected on Christmas, magnets, and electric convulsion therapy.
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For pediatric patients, intravenous fluids are the most commonly cited products involved in medication errors that are reported to the USP.