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In 1864, the first barbiturate (barbituric acid) was synthesized.
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Disorders that may affect pharmacodynamics include genetic mutations, malnutrition, thyrotoxicosis, myasthenia gravis, Parkinson's disease, and certain forms of insulin-resistant diabetes mellitus.
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In 1886, William Bates reported on the discovery of a substance produced by the adrenal gland that turned out to be epinephrine (adrenaline). In 1904, this drug was first artificially synthesized by Friedrich Stolz.
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There are over 65,000 known species of protozoa. About 10,000 species are parasitic.
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Normal urine is sterile. It contains fluids, salts, and waste products. It is free of bacteria, viruses, and fungi.