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In 1844, Charles Goodyear obtained the first patent for a rubber condom.
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Disorders that may affect pharmacodynamics include genetic mutations, malnutrition, thyrotoxicosis, myasthenia gravis, Parkinson's disease, and certain forms of insulin-resistant diabetes mellitus.
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The immune system needs 9.5 hours of sleep in total darkness to recharge completely.
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In 2010, opiate painkllers, such as morphine, OxyContin®, and Vicodin®, were tied to almost 60% of drug overdose deaths.
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Excessive alcohol use costs the country approximately $235 billion every year.