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In most cases, kidneys can recover from almost complete loss of function, such as in acute kidney (renal) failure.
Medications that are definitely not safe to take when breastfeeding include radioactive drugs, antimetabolites, some cancer (chemotherapy) agents, bromocriptine, ergotamine, methotrexate, and cyclosporine.
The use of salicylates dates back 2,500 years to Hippocrates's recommendation of willow bark (from which a salicylate is derived) as an aid to the pains of childbirth. However, overdosage of salicylates can harm body fluids, electrolytes, the CNS, the GI tract, the ears, the lungs, the blood, the liver, and the kidneys and cause coma or death.
On average, someone in the United States has a stroke about every 40 seconds. This is about 795,000 people per year.
More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.