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For pediatric patients, intravenous fluids are the most commonly cited products involved in medication errors that are reported to the USP.
The first oral chemotherapy drug for colon cancer was approved by FDA in 2001.
When intravenous medications are involved in adverse drug events, their harmful effects may occur more rapidly, and be more severe than errors with oral medications. This is due to the direct administration into the bloodstream.
It is believed that the Incas used anesthesia. Evidence supports the theory that shamans chewed cocoa leaves and drilled holes into the heads of patients (letting evil spirits escape), spitting into the wounds they made. The mixture of cocaine, saliva, and resin numbed the site enough to allow hours of drilling.
Cancer has been around as long as humankind, but only in the second half of the twentieth century did the number of cancer cases explode.